Manufacturing & Supply Chain

Moderna, a biotechnology company pioneering messenger RNA (mRNA) therapeutics and vaccines, has announced the finalisation of a strategic partnership with the UK government to establish a state-of-the-art mRNA research, development, and manufacturing facility in the UK. This milestone follows the agreement in principle between Moderna and the UK government, announced in June 2022.

“Our new state-of-the-art facility will bring mRNA manufacturing to UK shores, providing the UK public with access to pandemic response capabilities through Moderna COVID-19 vaccines and future respiratory virus vaccine candidates,” said Stéphane Bancel, Chief Executive Officer of Moderna. “We look forward to being part of the UK’s world-renowned science and innovation community, contributing to the UK health ecosystem through significant investments in R&D activities and expanding our clinical trial footprint across the country.”

Once operational, the Moderna Innovation and Technology Centre (MITC) is intended to provide access to a domestically manufactured portfolio of future mRNA vaccines against respiratory viruses, pending regulatory assessment and licensure. In addition, the facility is intended to provide the UK with direct access to pandemic response capabilities, which will support the UK in its global efforts as part of its “100 Days Mission” to reduce the impact of future pandemics. As part of the ten-year partnership, Moderna will also support the UK’s mRNA health and science ecosystem.

“We are excited to continue our collaboration with the UK government and UK Health Security Agency to establish the UK as a world-leading mRNA center of excellence,” said Darius Hughes, Moderna’s General Manager for the UK. “When constructed, our facility will harness mRNA science with the aim of developing and manufacturing vaccines that have the potential to address future threats posed by respiratory viruses.”

Construction is expected to commence in early 2023, with the facility expected to become operational by 2025, subject to planning and regulatory approvals.

In over 10 years since its inception, Moderna has transformed from a research-stage company advancing programs in the field of messenger RNA (mRNA), to an enterprise with a diverse clinical portfolio of vaccines and therapeutics across seven modalities, a broad intellectual property portfolio in areas including mRNA and lipid nanoparticle formulation, and an integrated manufacturing plant that allows for rapid clinical and commercial production at scale. Moderna maintains alliances with a broad range of domestic and overseas government and commercial collaborators, which has allowed for the pursuit of both groundbreaking science and rapid scaling of manufacturing. Most recently, Moderna’s capabilities have come together to allow the authorized use and approval of one of the earliest and most effective vaccines against the COVID-19 pandemic.

Moderna’s mRNA platform builds on continuous advances in basic and applied mRNA science, delivery technology and manufacturing, and has allowed the development of therapeutics and vaccines for infectious diseases, immuno-oncology, rare diseases, cardiovascular diseases and auto-immune diseases. Moderna has been named a top biopharmaceutical employer by Science for the past eight years.